Recent Advances in Parkinsons Disease

<p>Section I: Genetic and molecular mechanisms of neurodegeneration in PD<br>1. Identifying PD-causing genes and genetic susceptibility factors: current approaches and future prospects<br>2. The impact of genetic research on our understanding of Parkinson's Disease<br>3. Unraveling the role of defective genes<br>4. What causes the death of dopaminergic neurons in Parkinson’s disease?<br>5. Intracellular Signaling Pathways In Dopamine Cell Death And Axonal Degeneration<br>6. Control of mitochondrial integrity in Parkinson’s Disease<br>7. Role of Post-Translational Modifications in Modulating the Structure, Function and Toxicity of α-synuclein: Implications for Parkinson’s Disease Pathogenesis and Therapies</p> <p>Section II: Cellular and system-level pathophysiology of the basal ganglia in P<br>8. The role of dopamine in modulating the structure and function of striatal circuits<br>9. Assemblies of glutamate receptor subunits with post-synaptic density proteins and their alterations in Parkinson’s disease<br>10. Adenosine-dopamine interactions<br>11. Maladaptive plasticity in L-DOPA-induced dyskinesia<br>12. Effects of GPi and STN inactivation on physiological, motor, cognitive and motivational processes in animal models of Parkinson's disease<br>13. Computational physiology of the basal ganglia in Parkinson’s disease<br>14. Neurocomputational models of motor and cognitive deficits in Parkinson's Disease</p>