Engineering and Manufacturing for Biotechnology

Editors' Preface. Part I: Upstream Processes and Fermentation. Pretreatment processes of molasses for the utilization in fermentation processes; G. Çalik, et al. Lactic acid fermentation of hemicellulose liquors and their activated carbon pretreatments; J. Perttunen, et al. Enzymic solubilisation of proteins from tropical tuna using alcalase and some biological properties of the hydrolysates; F. Guerard, et al. Influence of the experimental conditions on the hydrolysis process in fish hydrolysates; R. Ravallec-Ple, et al. Part II: Process Modelling. Mathematical modelling of microbial processes - Motivation and means; T. Agger, J. Nielsen. Macroscopic modelling of bioprocesses with a view to engineering applications; Ph. Bogaerts, R. Hanus. A Model discrimination approach for data analysis and experimental design; R. Takors, et al. Model based sequential experimental design for bioprocess optimisation - An overview; R. Berkholz, R. Guthke. Metabolic flux modelling as a tool to analyse the behavior of a genetically modified strain of Saccharomyces cerevisiae; J.M. Urrieta-Saltijeral, et al. Metabolic investigation of an anaerobic cellulolytic bacterium: Fibrobacter succinogenes; C. Creuly, et al. Part III: Integrated Processes. Crossflow ultrafiltration of Bacillus licheniformis fermentation medium to separate protease enzymes; S. Takaç, et al. Part IV: Monitoring and Control. Evaluating KLa during fermentation using many methods simultaneously; K. Pouliot, et al. Respiration quotient: estimation during batch cultivation in bicarbonate buffered media; R. Neeleman. Fermentation phase detection using fuzzy clustering techniques and neural networksfor improved control; T.K. Hamrita, S. Wang. Simulation, design and model based predictive control of photobioreactors; J.-F. Cornet, et al. Part V: Reactor Engineering. Bioreactors for space: biotechnology of the next century; I. Walther, et al. Part VI: Immobilisation and Permeabilisation. State of the art developments in immobilised yeast technology for brewing; C.A. Masschelein, J. Vandenbussche. Immobilized yeast bioreactor systems for brewing &endash; Recent achievements; V.A. Nedovic, et al. New matrices and bioencapsulation processes; U. Jahnz, et al. Part VII: Downstream Processing. Industrial downstream processing; M. Laustsen. Separation of &agr;-lactalbumin and &bgr;-lactoglobulin by preparative chromatography using simulated moving beds; S.L. Lucena, et al. High-speed pectic enzyme fractionation by immobilised metal ion affinity membranes; S.A. Camperi, et al. Part VIII: Economic Finalities. Economic benefits of the application of biotechnology &endash; Examples; M. Etschmann, et al. Enzyme stability and stabilisation: applications and case Studies; G.A. Drago, T.D. Gibson. Improvements of enzyme stability and specificity by genetic engineering; M. Pohl, M.-R. Kula. An approach to desiccation-tolerant bacteria in starter culture production; F. Weekers, et al. Biotechnological research and the dairy industry; H. Neubauer, B. Mollet. Immobilised cell technology in winery and fruit wine production; R. Cachon, C. Divies. A new polysaccharide derived from plant rhizosphere: production, purification and physico-chemical properties; J.M. Crompin, et al. Initiation, growth and immobilisation of cell cultures of Taxus spp. for placlitaxel production; C.W. Tang,<