Separation Processes in Biotechnology

Series Introduction -- Foreword (Alan S. Michaels) -- Preface -- I Separation Processes -- 1 Selection of Operations in Separation Processes /Juan A. Asenio -- 2 Chemical, Physical, and Biochemical Concepts in Isolation and Purification of Proteins /Milton T. W. Hearn and Birger Anspach -- II Product Release and Recovery -- 3 Protein Secretion Systems in Microbial and Mammalian Cells /Donald T. Moir and Jen-I Mao -- 4 Cell Disruption by Homogenizer /Cady R. Engler -- 5 Bead Mill Disruption /Horst Schutte and Maria-Regina Kula -- 6 Enzymatic Cell Lysis for Product Release /Juan A. Asen;o and Barbara A. Andrews -- 7 Chemical Permeabilization of Cells for Intracellular Product Release /Thomas J. Naglak, David J. Hettwer, and Henry Y. Wang -- III Concentration and Separation Operations -- 8 Membrane Systems /A. G. Fane and J. M. Radovich -- 9 Ion -Exchange Processes /Charles D. Shuey -- 10 Aqueous Two-Phase Separations /Per-Jke Albertsson, Cote Johansson, and Folke T jerneld -- 11 Precipitation /Charles E. Glatz -- IV Purification Operations -- 12 Ion Exchange in Purification /Nien-Hwa Linda Wang -- 13 Process Affinity Chromatography /Yannis D. Clonis -- 14 Reversed-Phase and Hydrophobic Interaction Chromatography of Peptides and Proteins /Ziad El Rossi, Ann L. Lee, and Csaba Horvath -- 15 Analysis of Effluent Profiles in Large-Scale Liquid Chromatography /J. Hong -- 16 Electrically Driven Separation Processes: Analytical and Preparative Methods /Cornelius F. Ivory -- V Design of Separation Processes -- 17 Synthesis of Downstream Processes /George J. Prokopakis and Juan A. Asenjo -- 18 Automation in Protein Purification: The Use of Expert Systems for Control of Process Chromatography /Andrew C. Kenney -- 19 Downstream Processing Plant and Equipment /M. P. Brocklebank -- 20 Downstream Process Economics /Rajiv Datar and Carl-Gustaf Rosen -- Index.