John H. McNeill,
Christopher H. McIntosh,
Ramaswamy Subramanian,
Gary D. Lopaschuk,
Costas Ioannides,
Edward H. Leiter,
Brian B. Rodrigues,
Subodh Verma,
Violet Yuen,
Patrick Poucheret,
Fuad N. Ziyadeh,
Raymond A. Pederson,
P. R. Flatt,
Stephen W. Schaeffer,
Mahmood Mozaffari,
Catherine J. Field,
William C. Stanley,
Krista Kivilo,
Kumar Sharma,
Dong Cheol Han,
Andras Mogyorosi,
K.M. MacLeod,
R. Anthony Hebden,
Ivan C. Gerling,
Jeffrey C. Flynn,
John E. Sevee
e.a.
Experimental Models of Diabetes
Gebonden Engels 1999 1e druk 9780849316678
Verwachte levertijd ongeveer 11 werkdagen
Samenvatting
An extremely useful text for research Internationally renowned experts describe the models, provide data obtained with those models, and discuss the relative usefulness of models in relation to the diabetic syndrome in humans. The first section examines the most widely used model, the streptozotocin (STZ) rat, condensing a massive quantity of literature to present both the general effects of of STZ diabetes and the effects on individual organ systems. The second section discusses less well-known and more recent diabetic models, such as the BB rat, the NOD mouse and Zucker and Zucker Diabetic Fatty rat models.
Genetic models of insulin dependent diabetes mellitus (IDDM) are examined and compared to chemically induced IDDM models.
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