Myrtle A. Davis
Apoptosis Methods in Pharmacology and Toxicology
Approaches to Measurement and Quantification
Gebonden Engels 2002 2002e druk 9780896038905Levertijd ongeveer 9 werkdagen
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Samenvatting
Dr. Myrtle A. Davis has assembled a panel of cutting-edge scientists to describe their best methods for detecting, illuminating, and quantifying apoptotic mechanisms in a way that is useful for the design of toxicology and pharmacology studies. These state-of-the-art techniques include flow cytometric, fluorometric, and laser scanning methods for quantifying and characterizing apoptosis, as well as protocols for the use of DNA microarray technology, high throughput screens, and ELISA. Immunocytochemical methods for measuring biochemical and molecular endpoints in tissue sections will be highly useful for those carrying out studies in whole animal models as opposed to cell culture systems.
Specificaties
ISBN13:9780896038905
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:156
Uitgever:Humana Press
Druk:2002
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Inhoudsopgave
Flow Cytometric and Fluorometric Methods of Quantifying and Characterizing Apoptotic Cell Death.- Analysis of Apoptosis by Laser-Scanning Cytometry.- Specific Methods for Detection and Quantification of Apoptosis in Tissue Sections.- DNA Microarrays.- Microarray Analysis of Apoptosis.- ELISAs for Quantification of Bcl-2 Family Activities and Active Caspases.
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