Matthew Lee,
Matthew (Montefiore Medical Center and Albert Einstein College of Medicine) Lee,
Fawzi Abu Rous,
Fawzi (Henry Ford Health System) Abu Rous,
Alain Borczuk,
Alain (Weill Cornell Medicine) Borczuk,
Stephen (Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC) Liu,
Shirish (Henry Ford Health System) Gadgeel,
Balazs (Montefiore Medical Center and Albert Einstein College of Medicine) Halmos
e.a.
Targeting Oncogenic Driver Mutations in Lung Cancer
Paperback Engels 2023 9781009336130Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
The recent advances in the field of molecular diagnostic techniques have led to the identification of targetable alterations prompting a paradigm shift in the management of non-small cell lung cancer (NSCLC) and an era of precision oncology. This Element highlights the most clinically relevant oncogenic drivers other than EGFR, their management and current advancements in treatment. It also examines the different challenges in resistance to targeted therapies and diagnostic dilemmas for each oncogenic driver and the future direction of NSCLC management.
Specificaties
ISBN13:9781009336130
Taal:Engels
Bindwijze:Paperback
Aantal pagina's:75
Uitgever:Cambridge University Press
Serie:Elements in Molecula
Lezersrecensies
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Inhoudsopgave
1. Introduction; 2. ALK gene rearrangements; 3. ROSI gene rearrangements; 4. RET gene rearrangements; 5. MET alterations; 6. KRAS point mutations; 7. B-RAF point mutations; 8. NTRK1/2/3 gene fusions; 9. ERBB2 (HER2) mutations; 10. Diagnostic strategies; References.
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