Gene Delivery Systems

Development and Applications

Paperback Engels 2024 1e druk 9781032029726
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Samenvatting

This unique volume in our Drugs and Pharmaceutical Sciences series covers the development of gene therapy today, the technology involved, clinical applications of siRNA, non-viral vector-based mRNA delivery using nanotechnology, and RNA based vaccines for treating the infectious diseases. It also presents the current application of the CRISPR/Cas9 gene-editing technique which has revolutionized genome editing and which was awarded the 2020 Nobel Prize in Chemistry. Several new drug delivery systems are explored for the applications of gene therapy. These are found to be useful in treating chronic illnesses, including cancer and infectious diseases.

Key Features:

Overview of the development of gene therapy

Provides the most up to date information on the development of gene therapy, from the technology involved to gene correction and genome editing

Presents CRISPR gene therapy recent trends and applications

Discusses siRNA, mRNA, and DNA plasmids

Specificaties

ISBN13:9781032029726
Taal:Engels
Bindwijze:Paperback
Aantal pagina's:300
Uitgever:CRC Press
Druk:1

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Inhoudsopgave

Preface. About the Editor. List of Contributors. Overview of Development of Gene Therapy. Understanding the Technologies Involved in Gene Therapy. Gene Therapy and Gene Correction: Target, Progress and Challenges to Treat Human Diseases. Clinical Applications of siRNA. Human Genomics Projects, Gene Therapy and Precision Medicine. The Current State of Non-Viral Vector–Based mRNA Medicine Using Various Nanotechnology Applications. RNA-Based Vaccines for Infectious Disease. Conditional Replication of Oncolytic Virus Based on Detection of Oncogenic mRNA. Unilateral Ex Vivo Gene Therapy by GDNF in Neurodegenerative Diseases. Gene Therapy for Cancer Treatment: Recent Trends and Clinical Evidence. Gene Therapy for Retina and Eye Diseases. COVID-19 Vaccine Development and Applications. In Vivo Gene Therapy: AAV2 Vectors. Gene Therapy for Acquired Tissue Damage: Scope, Quality, Non-Clinical and Clinical Guidelines of Gene Therapy Medical Products. iMRI for Clinical Gene Therapy. Index.

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