Landmark Experiments in Protein Science

Gebonden Engels 2023 9781032458687
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Proteins are the workhorses of cells, performing most of the important functions which allow cells to use nutrients and grow, communicate among each other, and importantly, die if aberrant behavior is detected. How were proteins discovered? What is their role in cells? How do dysfunctional proteins give rise to cancers? Landmark Experiments in Protein Science explores the manner in which the inner workings of cells were elucidated, with a special emphasis on the role of proteins. Experiments are discussed in a manner as to understand what questions were being asked that prompted the experiments and what technical challenges were faced in the process; and results are presented and discussed using primary data and graphs.

Key FeaturesDescribes landmark experiments in cell biology and biochemistryDiscusses the "How" and "Why" of historically important experimentsIncludes primary, original data and graphsEmphasizes biological techniques, that help understand how many of the experiments performed were possibleDocuments, chronologically, how each result fed into the next experiments

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Inhoudsopgave

Chapter 1: Prelude to Biology: A History of Chemistry

Chapter 2: The Cell and Heredity

Chapter 3: Discovery of Proteins and Enzymes

Chapter 4: Protein and DNA Subunits

Chapter 5: The Energy of Cells: Glycolysis and the Krebs Cycle

Chapter 6: Protein and DNA Structure

Chapter 7: Protein Synthesis Part I: Localization of Protein Translation

Chapter 8: Protein Synthesis Part II: The Mechanism of Protein Translation

Chapter 9: The Energy of Cells: Oxidative Phosphorylation

Chapter 10: The Energy of Cells: The Mechanism of ATP Synthesis

Chapter 11: Techniques

Chapter 12: Cell Signaling Part I: The role of Phosphorylation

Chapter 13: Cell Signaling Part II: G-protein-coupled Receptors

Chapter 14: The Secretory Pathway

Chapter 15: The Mechanism of Cell Death

Chapter 16: The Biology of Cancer

Index

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          Landmark Experiments in Protein Science