Chimeric Antigen Receptor T Cells

CAR-T Cells for Cancer Treatment: Current Design and Next Frontiers.-&nbsp;Selection of Antibody Fragments for CAR-T Cell Therapy from Phage Display Libraries.-&nbsp;Phase I/II Manufacture of Lentiviral Vectors under GMP in an Academic Setting.-&nbsp;Production of Lentivirus for the Establishment of CAR-T Cells.-&nbsp;Optimized Production of Lentiviral Vectors for CAR-T Cell.-&nbsp;Lentiviral Vectors Production in Suspension Culture Using Serum-Free Medium for the Transduction of CAR-T Cells.-&nbsp;In vitro Transcribed (IVT)-mRNA CAR Therapy Development.-&nbsp;Generation of Chimeric Antigen Receptor T Cells Using Gammaretroviral Vectors.-&nbsp;Generation of CAR+ T Lymphocytes using the Sleeping Beauty Transposon System.-&nbsp;Platforms for Clinical-grade Car-T Cell Expansion.-&nbsp;CAR-T Cell Expansion in a Xuri Cell Expansion System W25.-&nbsp;Methods and Process Optimization for Large Scale CAR T Expansion Using the G-Rex Cell Culture Platform.-&nbsp;Replication Competent LentivirusAnalysis of Vector Transduced T Cell Products used in Cancer Immunotherapy Clinical Trials.-&nbsp;Immunophenotypic Analysis of CAR-T Cells.-&nbsp;Approaches of T Cell Activation and Differentiation for CAR-T Cell Therapies.-&nbsp;Determination of Cytotoxic Potential of CAR-T Cells in Co-cultivation Assays.-&nbsp;Analysis of CAR-mediated Tonic Signaling.-&nbsp;Generation&nbsp;of Tumor Cells Expressing Firefly Luciferase (fLuc) to Evaluate the Effectiveness of CAR in a Murine Model.-&nbsp;Analysis of Antitumor Effects of CAR-T Cells in Mice with Solid Tumors.<p><br></p>