Group A Streptococcus

<p>Detection of Streptococcus pyogenes Virulence Factors.-&nbsp;Closed-Tube Multiplex Real-Time PCR for the Detection of Group A Streptococcal Superantigens.-&nbsp;The emm-cluster Typing System.-&nbsp;Protocols for Tn-seq Analyses in The Group A Streptococcus.-&nbsp;Genetic Manipulation of Group A Streptococcus – Gene Deletion by Allelic Replacement.-&nbsp;Generation of Bioluminescent Group A Streptococcus for Biophotonic Imaging.-&nbsp;Whole Genome Sequence Analysis and Population Genomics of Group A streptococci.-&nbsp;Group A Streptococcus Transcriptome Analysis.-&nbsp;Protocol for Proteome Analysis of Group A Streptococcus.-&nbsp;Investigation of Group&nbsp;A Streptococcal Interactions with Host Glycan Structures using High Throughput Techniques: Glycan Microarray Analysis using Recombinant Protein and Whole Cells.-&nbsp;Using Lactococcus lactis as Surrogate Organism to Study Group A Streptococcus Surface Proteins.-&nbsp;Expression and Purification of Collagen-like Proteins of Group A Streptococcus.-&nbsp;Detection of Fibronectin-binding Proteins of Streptococcus pyogenes using Ligand Blot Analysis.-&nbsp;Morphology and Ultrastructure of Group A Streptococcus&nbsp; Biofilms.-&nbsp;Dynamic Interactions of Group A Streptococcus with Host Macrophages.-&nbsp;Identification of Group A Streptococcus-containing&nbsp;autophagosome-like&nbsp;vacuoles.-&nbsp;Flow Cytometry-based Assays to Quantify Complement Deposition and Neutrophil Uptake of Group a Streptococcus.-&nbsp;Live Cell Microscopy and Flow Cytometry to study Streptolysin S Mediated Erythrocyte Hemolysis.-&nbsp;Isolation of Monoclonal Antibodies to Group A Streptococcus Antigens Using Phage Display.-&nbsp;Assays to Analyse Adhesion of Group A Streptococcus to Host Cells.-&nbsp;The use of Galleria mellonella (wax moth) as an Infection Model for Group A Streptococcus.-&nbsp;A Superficial Skin Scarification Method in Mice to Mimic Streptococcus pyogenes Skin Infection in Humans.-&nbsp;A Mouse Nasopharyngeal Colonisation Model for Group A Streptococcus.-&nbsp;Humanised Plasminogen Mouse Model to Study Group A Streptococcus Invasive Disease.-&nbsp;Lacefield Whole Blood Killing Assay to Evaluate Vaccine Efficacy.-&nbsp;An Opsonophagocytic Killing Assay for the Evaluation of Group A Streptococcus Vaccine Antisera.-&nbsp;Validation of Suitable Carrier Molecules and Target Genes for antisense Therapy using Peptide-coupled Peptide Nucleic Acids (PNAs) in Streptococci.-&nbsp;Interfering with the Folding of Group A Streptococcal pili Proteins.-&nbsp;Use of Streptolysin O (SLO) to Study the Function of Lipid Rafts.-&nbsp;Engineering of Group A Streptococcus Isopeptide Bonds into Immunoglobulin-like Protein Domains.</p>

<p><br></p>

<p>&nbsp;</p>