PDZ Mediated Interactions

<div>Identification of PDZ Interactions by Yeast Two-Hybrid.-&nbsp;Identification of PDZ Interactions by Affinity Purification and Mass Spectrometry Analysis.-&nbsp;Identification of PDZ Interactions by Proteomic Peptide Phage Display.-&nbsp;A Computational Protocol to Analyze PDZ/PBM Affinity Data Obtained by High-Throughput Holdup Assay.-&nbsp;Study of PDZ-Peptide and PDZ-Lipid Interactions by Surface Plasmon Resonance/BIAcore.-&nbsp;PDZ Sample Quality Assessment by Biochemical and Biophysical Characterizations.-&nbsp;Crystallographic Studies of PDZ Domain-Peptide Interactions of the Scribble Polarity Module.-&nbsp;A Fluorescence-Based Assay to Determine PDZ-Ligand Binding Thermodynamics.-&nbsp;Unveiling the Folding Mechanism of PDZ Domains.-&nbsp;Development of Peptide-Based PDZ Domain Inhibitors.-&nbsp;Dynamic Control of Signaling by Phosphorylation of PDZ Binding Motifs.-&nbsp;Chemical Synthesis of PDZ Domains.-&nbsp;Viral PDZ Binding Motifs Influence Cell Behavior through the Interaction with Cellular Proteins Containing PDZ Domains.-&nbsp;Computational Design of PDZ:peptide Binding.-&nbsp;Mechanoregulation of PDZ Proteins, An Emerging Function.-&nbsp;Rational Design of PDZ Domain Inhibitors: Discovery of Small Organic Compounds Targeting PDZ Domains.</div>