RNA Structure and Dynamics

Co-transcriptional Assembly and Native Purification of Large RNA-RNA Complexes for Structural Analyses.-&nbsp;Probing RNA Structures and Interactions using Fluorescence Lifetime Analyses.-&nbsp;Characterizing Fluorescence Properties of Turn-on RNA Aptamers.-&nbsp;Probing Transient Riboswitch Structures via Single Molecule Accessibility Analysis.-&nbsp;Isothermal Titration Calorimetry Analysis of a Cooperative Riboswitch using an Interdependent-Sites Binding Model.-&nbsp;Application of Molecular Dynamics to Expand Docking Program’s Exploratory Capabilities and to Evaluate Its Predictions.-&nbsp;Exploring the Binding Process of Cognate Ligand to add Adenine Riboswitch Aptamer by using Explicit Solvent Molecular Dynamics (MD) Simulation.-&nbsp;Prediction of Dynamic RBP-RNA Interactions using PrismNet.-&nbsp;High-resolution Atomic Force Microscopy Imaging of RNA molecules in solution.-&nbsp;3D Structural Analysis of Long Non-coding RNA by Small Angle X-ray Scattering and Computational Modeling.-&nbsp;Combining Biophysical Methods for Structure-function Analyses of RNA in Solution.-&nbsp;Near-Atomic Resolution Cryo-EM Image Reconstruction of RNA.-&nbsp;Auto-DRRAFTER: Automated RNA Modeling Based on Cryo-EM Density.-&nbsp;X-ray Crystallography to Study Conformational Changes in a TPP Riboswitch.-&nbsp;Preparation of RNA Microcrystals for Serial Femtosecond Crystallography Experiments.-&nbsp;Mix-and-Inject Serial Femtosecond Crystallography to Capture RNA Riboswitch Intermediates.<p><br></p>