Antibiotics

Antibiotics - precious goods in changing times.-&nbsp;A Whole-Cell Assay for Detection of Antibacterial Activity in Actinomycetes Culture Supernatants.-&nbsp;Sampling of Human Microbiomes to Screen for Antibiotic-Producing Commensals.-&nbsp;Production of Antimicrobial Compounds by Homologous and Heterologous Expression.-&nbsp;Isolation and Purification of Natural Products from Microbial Cultures.-&nbsp;Structure Elucidation of Antibiotics.-&nbsp;Computer-Aided Drug Design – An update.-&nbsp;Cytotoxicity Assays as Predictors of the Safety and Efficacy of Antimicrobial Agents.-&nbsp;Microscopy-based Multiwell Assay to Characterize Disturbed Bacterial Morphogenesis Upon Antibiotic Action.-&nbsp;Expansion Microscopy of Bacillus subtilis.-&nbsp;Tracking global and local changes in membrane fluidity through fluorescence spectroscopy and microscopy.-&nbsp;Quantitative analysis of microscopy data to evaluate bacterial responses to antibiotic treatment.-&nbsp;Application of a Bacillussubtilis whole-cell biosensor (P_liaI-lux) for the identification of cell wall active antibacterial compounds.-&nbsp;Determination of Bacterial Membrane Impairment by Antimicrobial Agents.-&nbsp;A colorimetric assay to identify and characterize bacterial primase inhibitors.-&nbsp;Cell-based fluorescent screen amenable to HTS to Identify Inhibitors of Bacterial Translation Initiation.-&nbsp;­Bacterial two component systems: Overexpression, purification − in vitro and in vivo inhibitor screens.-&nbsp;Sample preparation for mass-spectrometry based absolute quantification of bacterial proteins in antibiotic stress research.-&nbsp;Elemental analysis for the characterization of antimicrobial effects.-&nbsp;label-free quantitation of ribosomal proteins from bacillus subtilis for antibiotic research.-&nbsp;Functional Metagenomics to Study Antibiotic Resistance.<p><br></p>