Pseudomonas aeruginosa

CRISPR/Cas9-based genome editing of Pseudomonas aeruginosa.- Investigating Pseudomonas aeruginosa Gene Function During Pathogenesis using Mobile-CRISPRi.- Engineering green-light-responsive heterologous gene expression in Pseudomonas.- Fluorescence-based evaluation of cyclic di-GMP levels in Pseudomonas aeruginosa.- Whole-cell biosensors for qualitative and quantitative analysis of quorum sensing signal molecules and the investigation of quorum quenching agents.- A Pseudomonas aeruginosa-suitable fluorescent reporter system for analyzing small RNA-mediated regulation of target mRNAs.- The Pseudomonas aeruginosa resistome: permanent and transient antibiotic resistance, an overview.- Biosensors for inducers of transient antibiotic resistance.- Pseudomonas aeruginosa soluble pyocins as antibacterial weapons.- Assays for studying Pseudomonas aeruginosa secreted proteases.- Single microcolony diffusion analysis in Pseudomonas aeruginosa biofilms.- Broad genome sequencing of environmental and clinical strains and genotyping.- Genome-scale analysis of the structure and function of RNA pathways and networks in Pseudomonas aeruginosa.- In-depth quantitative proteomics analysis of the Pseudomonas aeruginosa secretome. Improving the predictive value of preclinical mouse models of Pseudomonas aeruginosa respiratory infection to evaluate antibiotic efficacy.- Emerging in vitro models for the study of infection and pathogenesis of Pseudomonas aeruginosa and testing of antibacterial agents.