Human Genetics: The Basics
Gebonden Engels 2016 2e druk 9781138668003Samenvatting
Human genetics has blossomed from an obscure biological science and explanation for rare disorders to a field that is profoundly altering health care for everyone. This thoroughly updated new edition of Human Genetics: The Basics provides a concise background of gene structure and function through the lens of real examples, from families living with inherited diseases to population-wide efforts in which millions of average people are learning about their genetic selves. The book raises compelling issues concerning:
• The role of genes in maintaining health and explaining sickness
• Genetic testing, gene therapy, and genome editing
• The common ancestry of all humanity and how we are affecting our future.
Written in an engaging, narrative manner, this concise introduction is an ideal starting point for anyone who wants to know more about genes, DNA, genomes, and the genetic ties that bind us all.
Specificaties
Lezersrecensies
Inhoudsopgave
Acknowledgements
Abbreviations
Chapter 1. From Mendel’s Peas to Double Helices
From Genes to Genomes
Agriculture is Applied Genetics
Mendel’s Experiments —The Mystery of the Missing Traits
The Chromosome Connection
In Pursuit of the Genetic Material
Chapter 2. How Genes Work
A Brief History of CF
Mikayla’s Story
The Individual Level: Tissues and Organs
The Family Level
The Population
Chapter 3. Genes and Health
A Genomic View of Health
Causes of Death – An Organizing Framework
Cancer: The Cell Cycle Out of Control
The Microbiome and Infectious Disease
Chapter 4. Genetic Testing
The First Generation of Genetic Tests: Proteins
The Second Generation of Genetic Tests: DNA
The Third Generation of Genetic Tests: Exomes and Genomes
Chapter 5. Gene Therapy and Genome Editing
Protein Therapy Came First
Gene Therapy
Gene and Genome Editing
Chapter 6. From Ancestry to Destiny
DNA as Clock and Compass
The First Hominins
DNA Evidence Overlaps Fossil Evidence
Expansion Out of Africa
From Archaic Humans to Modern Humans
Into Europe
Genetic Genealogy and Ancestry Testing
The Future: Will Humanity Homogenize or Diverge?
Glossary
Bibliography
Index
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