Randy J. Read,
Joel L. Sussman
Evolving Methods for Macromolecular Crystallography
The Structural Path to the Understanding of the Mechanism of Action of CBRN Agents
Paperback Engels 2007 2007e druk 9781402063152
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallization through data collection, structure solution and analysis. The book shows how modern high-throughput methods are contributing to a deeper understanding of medical problems.
Specificaties
ISBN13:9781402063152
Taal:Engels
Bindwijze:paperback
Aantal pagina's:192
Uitgever:Springer Netherlands
Druk:2007
Lezersrecensies
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Inhoudsopgave
Preface.
Succeeding with Seeding: some practical Advice; T. Bergfors.-
Expression, Purification and Crystallisation of membrane Proteins; Bernadette Byrne.-
Macromolecular Cryo-Crystallography; E. Garinan.-
Processing Diffraction Data with Mosfim; A.G. W. Leslie and H.R. Powell.-
SAD Phasing: basic Concepts and High-Throughput; G.M. Sheldrick.-
Likelihood-based experimental phasing in Phaser; A.J. McCoy, L. C. Storoni and R. J. Read.-
Stochastic molecular Replacement; N. M. Glykos.-
Likelihood-based molecular Replacement in Phaser; R. J. Read et al.-
Automated Structure Determination with PHENIX ; P. D. Adam et al.-
Density Modification in MAIN; D. Turk.-
Ab initio Phasing starting from Low Resolution; V.Lunin et al.
Structural Genomics of Mycobacterium tuberculosis - a Search for Function and new Drug Targets; T. Baker.-
3D Domain Swapping and its Relevance to conformational Diseases; M. Jaskolski.-
Structural Bioinformatics: From PROTEIN Structure to Function; J.D. Watson et al.-
Single-particle Imaging; D. Sayre.-
Succeeding with Seeding: some practical Advice; T. Bergfors.-
Expression, Purification and Crystallisation of membrane Proteins; Bernadette Byrne.-
Macromolecular Cryo-Crystallography; E. Garinan.-
Processing Diffraction Data with Mosfim; A.G. W. Leslie and H.R. Powell.-
SAD Phasing: basic Concepts and High-Throughput; G.M. Sheldrick.-
Likelihood-based experimental phasing in Phaser; A.J. McCoy, L. C. Storoni and R. J. Read.-
Stochastic molecular Replacement; N. M. Glykos.-
Likelihood-based molecular Replacement in Phaser; R. J. Read et al.-
Automated Structure Determination with PHENIX ; P. D. Adam et al.-
Density Modification in MAIN; D. Turk.-
Ab initio Phasing starting from Low Resolution; V.Lunin et al.
Structural Genomics of Mycobacterium tuberculosis - a Search for Function and new Drug Targets; T. Baker.-
3D Domain Swapping and its Relevance to conformational Diseases; M. Jaskolski.-
Structural Bioinformatics: From PROTEIN Structure to Function; J.D. Watson et al.-
Single-particle Imaging; D. Sayre.-
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