Designs for Clinical Trials

Perspectives on Current Issues

Paperback Engels 2013 2012e druk 9781461429531
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Samenvatting

This book will examine current issues and controversies in the design of clinical trials, including topics in adaptive and sequential designs, the design of correlative genomic studies, the design of studies in which missing data is anticipated.  Each chapter will be written by an expert conducting research in the topic of that chapter.  As a collection, the chapters would be intended to serve as a guidance for statisticians designing trials.

Specificaties

ISBN13:9781461429531
Taal:Engels
Bindwijze:paperback
Aantal pagina's:206
Uitgever:Springer New York
Druk:2012

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Inhoudsopgave

New designs for phase I dose finding studies.- Phase II/III designs for trials.- Design issues for clinical studies with genomic measurements.- Designing studies with longitudinal measurements subject to dropout.- Issues in sample size re-estimation.- Adaptive designs.- The design of non-inferiority trials.- Issues in the design of HIV prevention trials.- Randomization algorithms.- Sequential designs for phase III studies.- Case studies of difficult designs.- Ethical issues in the design of trials.- Index.

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        Designs for Clinical Trials