Stem Cells and Prostate Cancer

Gebonden Engels 2013 2013e druk 9781461464976
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

​​​​Recent evidence demonstrates that normal prostate tissue contains stem cells.  There is also accumulating evidence that prostate cancer contains a population of cells with stem cell-like characteristics referred to as cancer stem cells, or tumor initiating cells.  Both the normal prostate stem cell and cancer stem cell populations have important implications for the generation, therapeutic targeting, and prevention of prostate cancer.  The purpose of this book is to explore the role of stem cells in prostate cancer, which is becoming an increasingly hot trend in cancer research. ​

Specificaties

ISBN13:9781461464976
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:182
Uitgever:Springer New York
Druk:2013

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Inhoudsopgave

Preface.- Stem Cells and Prostate Development.- Isolation and Characterization of Prostate Stem Cells.- Prostate tumor initiating cells.- TIC Markers and methods of characterization.- Genetic Control of Self Renewal of the TIC.- Therapeutic targeting of the prostate TIC.- The prostate stem cell niche.- Tumor stroma control of the prostate TIC.- Targeting the prostate stem cell for chemoprevention.- Stem cell models for functional validation of prostate cancer genes.- Index​.

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        Stem Cells and Prostate Cancer