Sperm Chromatin for the Clinician

Part I: Biological Determinants of Sperm Chromatin Damage.- Sperm Chromatin: An Overview.- Spermatogenesis: An Overview.- Role of Oxidative Stress in the Etiology of Sperm DNA Damage.- Abortive Apoptosis and Sperm Chromatic Damage.- Spermiogenesis in Sperm Genetic Integrity.- Part II: Clinical Aspects of Sperm Chromatin Damage.- Male Subfertility and Sperm Chromatin Damage.- Aging and Sperm DNA.- Cancer in Males: Implications for Sperm Quality, Fertility, and Progeny Outcome.- Sperm Chromatin and Environmental Factors.- Effects of Male Accessory Gland Infection on Sperm Parameters.- Antioxidants and Sperm DNA Damage.- Part III: Sperm Chromatin and Assisted Reproductive Technologies (ART).- The Impact of Sperm Processing and Cryopreservation on Sperm DNA Integrity.- Sperm Chromatin and ART (IUI, IVF and ICSI).- Sperm DNA Damage and Pregnancy Loss after IVF and ICSI.- Postnatal Effects of Sperm Chromatin Damage.- Evaluation of Chromatin and DNA Integrity in Testicular Sperm.- Clinical Utility of Sperm DNA Integrity Tests.