Rongling Wu
Quantitative Methods for Precision Medicine
Pharmacogenomics in Action
Gebonden Engels 2022 1e druk 9781482219456Levertijd ongeveer 11 werkdagen
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Samenvatting
Features:
Functional and systems mapping models to characterize the genetic architecture of multiple medication processes Statistical methods for analyzing informative missing data in pharmacogenetic association studies Functional graph theory of inferring genetic interaction networks from association data Leveraging the concept of epistasis to capture its bidirectional, signed and weighted properties Modeling gene-induced cell-cell crosstalk and its impact on drug response A graph model of drug-drug interactions in combination therapies Critical methodological issues to improve pharmacogenomic research as the cornerstone of precision medicine
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