BeadChip Molecular Immunohematology

An overview of the Classical Serological methods: limitations and benefits of serology and DNA testing.- Introduction to Molecular Typing.- The BeadChip System: A Flexible Array Format for Complex Nucleic Acid and Protein Analysis.- Implementation of HEA at Blood Centers: Prescreening, Rare Donors, Inventory Management.- Implementation of HEA BeadChip System at Medical Centers: Providing Extended Matched Units and Eliminating Complex Workups for Patients.- Human Platelet Antigen Genotyping and Diagnosis of Antiplatelet Alloimmunization.- Blood group genotyping by high-throughput DNA-analysis: Application to the Panel National de Référence du CNRGS.- Implementation and Assessment of High-Throughput Donor Typing at the Milan, Italy Immunohematology Reference Laboratory.- Implementation of the BioArray Erythrocyte Antigen (HEA) genotyping System BeadChip™ HEA: The Red Cross of Spain Experience.- Looking Beyond HEA: Matching SCD Patients for RH Variants
Marion E Reid*, Christine Halter Hipsky.- Identification of Altered RHD and RHCE Alleles: A Comparison of Manual and Automated Molecular Methods.- Bayesian Classification Algorithms for Automated Allele Assignment.