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Renal Cell Carcinoma

Translational Biology, Personalized Medicine, and Novel Therapeutic Targets

Paperback Engels 2014 2012e druk 9781489991393
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Samenvatting

This book provides a comprehensive look at renal cell carcinoma, exploring its biology as well as current and future molecular targets for renal cancer carcinoma.

Specificaties

ISBN13:9781489991393
Taal:Engels
Bindwijze:paperback
Aantal pagina's:328
Uitgever:Springer New York
Druk:2012

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Inhoudsopgave

Preface.- The Genetic Basis of Kidney Cancer and Implications for Targeted Therapies.- Molecular Biology of Clear Cell Renal Carcinoma.- HIF Biology in RCC:  Implications for Signaling, Disease Progression, and Treatment.- Tissue Biomarkers in Renal Cell Carcinoma: Intermediate Endpoints in the Selection of Targeted Agents for RCC.- Molecular Characterization of Renal Cell Carcinoma.- Targeting The Vegf Pathway In Renal Cell Carcinoma.- Angiopoetins and Other Non-VEGF Antiangiogenic Targets In Advanced Renal Cell Carcinoma.- Towards Personalized Cancer Medicine.- Epigenetic Targeting and Histone Deacetylase Inhibition in RCC.- C-MET as a Novel Target for the Treatment of Renal Cell Carcinoma.- Characterizing and Modulating the Tumor Micro-Environment in Renal Cell Carcinoma: Potential Therapeutic Strategies.- Carbonic Anhydrase IX:  Its role as a biomarker, diagnostic, and therapeutic target in Renal Cell Carcinoma.- Presurgical Therapy for Renal Cell Carcinoma and Implications for Window of Opportunity Trials.- Mechanisms of Resistance to VEGF Directed Therapy and Implications for Future Trial Design.- Vaccine Based Immunotherapy and Targeting the Tumor Microenvironment in Renal Cell Carcinoma.- Index.

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€ 180,99
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        Renal Cell Carcinoma