Steve Horvath
Weighted Network Analysis
Applications in Genomics and Systems Biology
Paperback Engels 2014 9781493900220Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
High-throughput measurements of gene expression and genetic marker data facilitate systems biologic and systems genetic data analysis strategies. Gene co-expression networks have been used to study a variety of biological systems, bridging the gap from individual genes to biologically or clinically important emergent phenotypes.
Specificaties
ISBN13:9781493900220
Taal:Engels
Bindwijze:paperback
Uitgever:Springer New York
Lezersrecensies
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Inhoudsopgave
Preface.- Networks and fundamental concepts.- Approximately factorizable networks.- Different type of network concepts.- Adjacency functions and their topological effects.- Correlation and gene co-expression networks.- Geometric interpretation of correlation networks using the singular value decomposition.- Constructing networks from matrices.- Clustering Procedures and module detection.- Evaluating whether a module is preserved in another network.- Association and statistical significance measures.- Structural equation models and directed networks.- Integrated weighted correlation network analysis of mouse liver gene expression data.- Networks based on regression models and prediction methods.- Networks between categorical or discretized numeric variables.- Networks based on the joint probability distribution of random variables.- Index.
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