Christiane Ferran
The Multiple Therapeutic Targets of A20
Gebonden Engels 2014 2014e druk 9781493903979
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
This book is meant to provide the most current knowledge regarding the mechanisms of action of A20, if its versatile functions and their validation in animal models of human disease and its promise as a diagnostic biomarker and therapeutic target.
Specificaties
ISBN13:9781493903979
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:188
Uitgever:Springer New York
Druk:2014
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Inhoudsopgave
A20—A Bipartite Ubiquitin Editing Enzyme with Immunoregulatory Potential.- The Biology of A20-Binding Inhibitors of NF- κB Activation (Abins).- The Biology of A20-Like Molecules.- Anti-Viral Tetris: Modulation of the Innate Anti-Viral Immune Response by A20.- A20 Expressing Tumors and Anticancer Drug Resistance.- Translational Studies of A20 in Atherosclerosis and Cardiovascular Disease.- A Biomarker of Allograft Outcome: A Showcase in Kidney Transplantation.- A20—An Omnipotent Protein in the Liver: Prometheus Myth Resolved?.- Emerging Roles for A20 in Islet Biology and Pathology.- Single Nucleotide Polymorphisms at the TNFAIP3/A20 Locus and Susceptibility/Resistance to Inflammatory and Autoimmune Diseases.
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