Chromothripsis

The Genomic Characteristics and Origin of Chromothripsis.- Clinical Consequences of Chromothripsis and Other Catastrophic Cellular Events.- Potential Role of Chromothripsis in the Genesis of Complex Chromosomal Rearrangements in Human Gametes and Preimplantation Embryo.- Chromothripsis and the Macroevolution Theory.- Analysis of Chromothripsis by Combined FISH and Microarray Analysis.- Chromothripsis Detectable in Small Supernumerary Marker Chromosomes (sSMC) Using Fluorescence In Situ Hybridization (FISH).- Identification of Chromothripsis in Biopsy Using SNP-Based Microarray.- Detection of Chromothripsis in Plants.- RNA-Seq Analysis to Detect Abnormal Fusion Transcripts Linked to Chromothripsis.- Experimental Determination of Checkpoint Adaptation by Mitotic Shake-Off and Microscopy.- A Role for Retrotransposons in Chromothripsis.- Generation of Micronuclei and Detection of Chromosome Pulverization.- Detection of Impaired DNA Replication and Repair in Micronuclei as Indicators of Genomic Instability and Chromothripsis.- Study of Telomere Dysfunction in TP53 Mutant LoVo Cell Lines as a Model for Genomic Instability.- Genes, Proteins, and Biological Pathways Preventing Chromothripsis.- Expression of Genes Associated with Telomere Homeostasis in TP53 Mutant LoVo Cell Lines as a Model for Genomic Instability.- Chromothripsis Detection and Characterization Using the CTLPScanner Web Server.- ChromothripsisDB: A Curated Database for the Documentation, Visualization, and Mining of Chromothripsis Data.- Time-Lapse Imaging for the Detection of Chromosomal Abnormalities in Primate Pre-Implantation Embryos.- Correlative Live Imaging and Immunofluorescence for Analysis of Chromosome Segregation in Mouse Preimplantation Embryos.- Experimental Induction of Genome Chaos.- Looking for Broken TAD Boundaries and Changes on DNA Interactions: Clinical Guide to 3D Chromatin Changes Analysis in Complex Chromosomal Rearrangements and Chromothripsis.<p></p>