Richard S. Larson
Bioinformatics and Drug Discovery
Gebonden Engels 2005 2006e druk 9781588293466
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
A collection of readily reproducible bioinformatic methods to advance the drug discovery process from gene identification to protein modeling to the identification of specific drug candidates. The authors demonstrate these techniques, including microarray analysis, the analysis of genes as potential drug targets, virtual screening and in silico protein design, and cheminformatics, in a variety of practical situations. Because these technologies are still emergent, each chapter contains an extended introduction that explains the theory and application of the technology and techniques described.
Specificaties
ISBN13:9781588293466
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:444
Uitgever:Humana Press
Druk:2006
Lezersrecensies
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Inhoudsopgave
New Strategies in Drug Discovery.- Basic Microarray Analysis.- From Microarray to Biological Networks.- Microarray Analysis in Drug Discovery and Clinical Applications.- Ontology-Driven Approaches to Analyzing Data in Functional Genomics.- Gene Evolution and Drug Discovery.- Standardization of Microarray and Pharmacogenomics Data.- Clinical Applications of Bioinformatics, Genomics, and Pharmacogenomics.- Protein Interactions Probed With Mass Spectrometry.- Discovering New Drug-Targeting Sites on Flexible Multidomain Protein Kinases.- Nuclear Magnetic Resonance-Based Screening Methods for Drug Discovery.- Receptor-Binding Sites.- In Silico Protein Design.- Chemical Database Preparation for Compound Acquisition or Virtual Screening.- Bioinformatics Platform Development.
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