Eric Verdin
Histone Deacetylases
Transcriptional Regulation and Other Cellular Functions
Gebonden Engels 2006 2006e druk 9781588294999Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
A panel of leading investigators summarizes and synthesizes the new discoveries in the rapidly evolving field of histone acetylation as a key regulatory mechanism for gene expression. The authors describe what has been learned about these proteins, including the identification of the enzymes, the elucidation of the enzymatic mechanisms of action, and the identification of their substrates and their partners. They also review the structures that have been solved for a number of enzymes-both alone and in complex with small molecule inhibitors-and the biological roles of the several histone deacetylases (HDAC) genes that have been knocked out in mice.
Specificaties
ISBN13:9781588294999
Taal:Engels
Bindwijze:Gebonden
Aantal pagina's:352
Uitgever:Humana Press
Druk:2006
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