Therapeutic Oligonucleotides

<p>1. Therapeutic Oligonucleotides</p><p>            John Goodchild</p><p> </p><p>2. Dinucleotides Containing 3¢-S-Phosphorothiolate Linkages</p><p>            James W. Gaynor and Richard Cosstick</p><p> </p><p>3. 2’-O,4’-C-Methyleneoxymethylene Bridged Nucleic Acids (2’,4’-BNACOC)</p><p>            Yoshiyuki Hari, Tetsuya Kodama, Takeshi Imanishi, and Satoshi Obika</p><p> </p><p>4. A Non-covalent Peptide-based Strategy for Ex-vivo and In vivo Oligonucleotide Delivery</p><p>            Laurence Crombez, May C. Morris, Frederic Heitz, and Gilles Divita</p><p> </p><p>5. Cell Penetrating Peptides-based Strategies for the Delivery of Splice Redirecting Antisense Oligonucleotides</p><p>            Samir El Andaloussi, Fatouma Said Hassane, Prisca Boisguerin, Rannar Sillard, Ulo Langel, and Bernard Lebleu</p><p> </p><p>6. A Nanoparticle for Tumor Targeted Delivery of Oligomers</p><p>            Xinrong Liu, Yi Wang, and Donald J. Hnatowich</p><p> </p><p>7. Light-directed Delivery of Nucleic Acids</p><p>            Sigurd Bøe, Lina Prasmickaite, Birgit Engesæter, and Eivind Hovig </p><p> </p><p>8. Antibody Targeted siRNA Delivery </p><p>            Masoud M. Toloue and Lance P. Ford</p><p> </p><p>9. Aptamer-Drug Conjugation for Targeted Tumor Cell Therapy</p><p>            Michael J. Donovan, Ling Meng, Tao Chen, Yunfei Zhang, Kwame Sefah, and Weihong Tan</p><p> </p><p>10. Five-step Process for Screening Antisense Compounds for Efficacy: Gene Target IL-12Rb2 </p><p>            Nikki B. Marshall, Laura L. Hauck, and Dan V. Mourich</p><p> </p><p>11. Diverse Small Non-coding RNAs in RNA Interference Pathways</p><p>            Liande Li and Yi Liu</p><p> </p><p>12. Quantification of siRNAs In vitro and In vivo </p><p>            Angie Cheng, Alexander V. Vlassov, and Susan Magdaleno</p><p> </p><p>13. Optimization of Transfection Conditions and Analysis of siRNA Potency Using Real-time PCR</p><p>            Angie Cheng, Susan Magdaleno, and Alexander V. Vlassov</p><p> </p><p>14. siRNA Knockdown of Gene Expression in Endothelial Cells</p><p>            Emily Dennstedt and Brad Bryan</p><p>15. Using RNA Interference in Schistosoma mansoni</p><p>            Rita Bhardwaj, Greice Krautz-Peterson, and Patrick J. Skelly</p><p> </p><p>16. Performing the Labeled microRNA Pull-down (LAMP) Assay System: An Experimental Approach for High-throughput Identification of microRNA-target mRNAs </p><p>            Ren-Jun Hsu and Huai-Jen Tsai </p><p> </p><p>17. Synthesis, Purification, and Characterization of Oligoribonucleotides that Act as Agonists of TLR7 and/or TLR8</p><p>            Tao Lan and Ekambar R. Kandimalla</p><p> </p><p>18. Synthesis, Purification, and Characterization of Immune-Modulatory Oligodeoxynucleotides that Act as Agonists of Toll-like Receptor 9</p><p>            Mallikarjuna Reddy Putta, Dong Yu, and Ekambar R. Kandimalla</p><p> </p><p>19. Surface Plasmon Resonance Investigation of RNA Aptamer-RNA Ligand Interactions</p><p>            Carmelo Di Primo, Eric Dausse, and Jean-Jacques Toulmé</p><p> </p><p>20. Practical Considerations for Analyzing Antigene RNAs (agRNAs): RNA Immunoprecipitation of Argonaute Protein</p><p>            Jacob C. Schwartz and David R. Corey</p><p> </p><p>21. Inhibition of Human Papillomavirus Expression Using DNAzymes</p><p>            María Luisa Benítez-Hess, Pablo Reyes-Gutiérrez, and Luis Marat Alvarez-Salas</p>