Roland Barret
Medicinal Chemistry
Fundamentals
Gebonden Engels 2018 9781785482885Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
Medicinal Chemistry: Fundaments presents the cycle of the life of drugs, their physico-chemical properties, and consequences that arise in development. The fundamental concepts of Medicinal Chemistry (pharmacophore, prodrugs, Lipinsky rules) are also presented, including discussions on specific concerns of the European Pharmacopeia – the industrialist’s bible – its role, and a description of the monographs of active principles.
Specificaties
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Inhoudsopgave
<p>1. Medicines and Drugs<br>2. Importance and Evaluation of the pKa<br>3. Importance and Evaluation of Lipophilicity<br>4. Importance and Evaluation of Solubility<br>5. Importance and Evaluation of the Polar Surface Area (PSA and TPSA)<br>6. Lipinski’s Rule of Five<br>7. Principle of a Prodrug<br>8. Pharmacophore<br>9. The European Pharmacopoeia</p>
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