New Frontiers: Extracellular Vesicles
Gebonden Engels 2021 9783030671709Samenvatting
The field of extracellular vesicles (EVs) has progressed immensely in recent times with evidences highlighting their importance in physiology and pathology. This book entails extensive reflective literature on many subtypes of EVs including exosomes, exomeres, ectosomes, apoptotic vesicles, bacterial EVs and fungal EVs.
The book further discusses the biogenesis and secretion of these EVs, detailing the biological pathways and proteins involved. Research investigating the biological functions of EVs is rapidly increasing and the current knowledge around their role in progression of diseases such as cancer, neurodegeneration and metabolic disorders is discussed in multiple chapters. The implications of EVs in intercellular communication and the significance of biologically active cargo carried within these EVs are further examined. Moreover, the numerous applications of EVs in diagnostics and treatment of diseases are reviewed in detail, particularly their potential as biomarkers and drug delivery vehicles.
Taken together, this book is a compilation of the key implications of EVs that are secreted by virtually all cell types. Readers will gain a perspective into the biology, functions and applications of EVs and their constantly evolving knowledge base.
Specificaties
Lezersrecensies
Inhoudsopgave
<p>Subtypes, Biogenesis, and Secretion of Extracellular Vesicles</p>
<p> </p>
<p>1. Introduction to the community of extracellular vesicles<br> Pamali Fonsekaa,*, Akbar L Marzana and Suresh Mathivanana<br> P.Fonseka@latrobe.edu.au</p>
<p>2. Biogenesis of extracellular vesicles<br> Taeyoung Kang, Ishara Atukorala and Suresh Mathivanan*<br> S.Mathivanan@latrobe.edu.au </p>
<p>3. The role of post-translational modifications in targeting protein cargo to extracellular vesicles<br> Ishara Atukorala* and Suresh Mathivanan<br> I.Atukorala@latrobe.edu.au</p>
<p>4. Apoptotic bodies: Mechanism of formation, isolation and functional relevance<br> Jascinta P. Santavanond, Stephanie F. Rutter, Georgia K. Atkin-Smith and Ivan K. H. Poon<sup><br> </sup>atkinsmith.g@wehi.edu.au , i.poon@latrobe.edu.au</p>
<p>5. Exomeres: A new member of extracellular vesicles family<br> Sushma Anand, Monisha Samuel and Suresh Mathivanan*<br> S.Mathivanan@latrobe.edu.au</p>
<p> </p>
<p>Functional Role and Clinical Implications of Extracellular Vesicles</p>
<p> </p>
<p>6. Bacterial membrane vesicles mediate pathogenesis in the human host<br> William J. Gilmore, Natalie Bitto & Maria Kaparakis-Liaskos*<br> m.liaskos@latrobe.edu.au</p>
<p>7. Fungal Extracellular Vesicles in Pathophysiology<br> Donovan Garcia-Ceron, Mark R. Bleackley , Marilyn A. Anderson (corresponding author)<br> m.anderson@latrobe.edu.au</p>
<p>8. Socially distanced intercellular communication: mechanisms for extracellular vesicle cargo delivery<br> Stephanie J. Popa and Sarah E. Stewart*<br> Sarah Stewart (ss2340@cam.ac.uk)</p>
<p>9. EXTRACELLULAR VESICLES IN CHEMORESISTANCE<br> Gabriele De Rubis and Mary Bebawy*<br> mary.bebawy@uts.edu.au</p>
<p>10. Extracellular vesicle – mediated vascular pathology in glioblastoma<br> Cristiana Spinelli, Nadim Tawil, Lata Adnani, Janusz Rak* & Dogsic Choi*<br> choi.dongsic@mail.mcgill.ca; janusz.rak@mcgill.ca</p>
<p>11. Extracellular vesicles regulate cancer metastasis<br> Sanjay Shahi, Cassandra Cianciarulo, Christina Nedeva* and Suresh Mathivanan*<br> S.Mathivanan@latrobe.edu.au</p>
<p>12. EXTRACELLULAR VESICLE-MEDIATED BONE REMODELING AND BONE METASTASIS: IMPLICATIONS IN PROSTATE CANCER<br> Kalyani C. Patil1, Carolina Soekmadji*<br> Carolina.Soekmadji@qimrberghofer.edu.au </p>
<p>13. Extracellular vesicles contain putative cancer biomarkers<br> Sai V. Chitti* and Christina Nedeva<br> S.Chitti@latrobe.edu.au</p>
<p>14. Engineering extracellular vesicles for cancer therapy<br> Christina Nedevaa,* and Suresh Mathivanana<br> C.Nedev@latrobe.edu.au</p>
<p>15. Extracellular vesicles in metabolism and metabolic diseases<br> Akbar L Marzan, Christina Nedeva* and Suresh Mathivanan*<br> S.Mathivanan@latrobe.edu.au</p>
<p>16. Extracellular vesicles in neurological disorders<br> Alex Mazurskyy and Jason Howitt*</p>
<p>17. Emerging Roles of Extracellular Vesicles derived Non-Coding RNAs in the Cardiovascular System<br> Ramasamy Subbiah, Divya Sridharan, Karthika Duairaj, K. Shanmugha Rajan, Mahmood Khan, Venkata Naga Srikanth Garikipati<br> venkata.garikipati@osumc.edu</p>
18. Extracellular vesicles and Preeclampsia - Current knowledge and future research directions<br> Carlos Palma, Jessica Jellins, Andrew Lai, Alexis Salas, America Campos, Shayna Sharma, Gregory Duncombe, Jon Hyett, Carlos Salomon<sup><br> </sup>c.salomongallo@uq.edu.au<p></p>
<p>19. The role of extracellular vesicles in sperm function and male fertility<br> Natalie J. Foot* and Sharad Kumar<br> Natalie.foot@unisa.edu.au</p>
<p>20. Extracellular Vesicles and Cerebral Malaria<br> Georges Emile Raymond GRAU & Elham HOSSEINI-BEHESHTI</p>
<p>21. Are dietary extracellular vesicles bioavailable and functional in consuming organisms?<br> Rahul Sanwlani, Pamali Fonseka and Suresh Mathivanan*<br> S.Mathivanan@latrobe.edu.au</p>
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