Ophthalmic Product Development

Introduction and History of Ophthalmic Product Development.- Ocular Surface Anatomy and Physiology: Impact on Product Development.- Anatomy and Physiology of the Anterior Chamber – Impact on Product Development.- Back of the eye anatomy & physiology – Impact on product development.- Physicochemical and Biological Fundamentals for Drug Delivery to the Eye.- Topical Ophthalmic Dosage Form Development – Key Components and Critical Quality Attributes.- &nbsp;Intra-ocular Injectable Dosage Form Development.- Microbiological Considerations for Ophthalmic Products – Sterility, Endotoxin Limits and Preservatives.- Packaging Development – Multi-dose container closure for preservative free products, extractable/leachables from packaging, new technologies.- Liquid ophthalmic drug products – physicochemical properties, formulations and manufacturing considerations.- Emulsions for topical eye delivery: state of the art and future perspectives.- Emulsions for topical eye delivery: state of the art and future perspectives.- Microparticle Products For The Eye - preformulation, formulation, and manufacturing considerations.- NANOPARTICLE PRODUCTS FOR THE EYE: preformulation, formulation and manufacturing considerations.- Advanced Hydrogel Formulations for the Eye.- Ophthalmic Product Development for Biologics.- Implantable Devices to Treat Ophthalmic Conditions –Drug Delivery Systems.- Development of Artificial Tears Products for Ocular Conditions.- Approval of Topical Ophthalmic Generic Products in the US – Simple to Complex Dosage Forms and Establishing Equivalency.- The development and commercialization of sustained-release ocular drug delivery technologies.- Manufacturing considerations and challenges for AAV Ocular Gene Therapy.- Transcorneal Kinetics of Topical Drugs and Nanoparticles.<br>