Macropinocytosis

Functions and Mechanisms

Gebonden Engels 2022 9783030940034
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This book presents the functions and mechanisms of macropinocytosis, an actin-driven endocytic uptake process.

Key points, including the evolutionary origins of macropinocytosis and major signaling pathways that regulate this uptake mechanism, are highlighted. A wide-array of functions of macropinocytosis are described, including cellular metabolism, cell death, cell migration and antigen presentation. Macropinocytosis has recently been recognized as a critical pathway in disease pathology and treatment. Therefore, a broad overview of macropinocytosis will benefit clinicians, as well as translational and basic research scientists. Moreover, as one of the main clathrin-independent endocytic routes, compiling all the critical information about macropinocytosis in one collection, this book will also be helpful to educators and their students.

Specificaties

ISBN13:9783030940034
Taal:Engels
Bindwijze:gebonden
Uitgever:Springer International Publishing

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Inhoudsopgave

<div>Table of Contents</div><div><br></div><div>Macropinocytosis – Functions and Mechanisms</div><div><br></div><div>Preface</div><div><br></div><div>Part 1: Functions of Macropinocytosis</div><div>1. Functional Diversity of Macropinocytosis - Mishra et al.&nbsp;</div><div>2. Macropinocytosis and Cancer: From Tumor Stress to Signaling Pathways - Lambies et al.</div><div>3. The amoebal model for micropinocytosis - Kay et al.</div><div>4. Extracellular ATP and macropinocytosis - Evers et al.</div><div>5. Macropinocytosis and Cell Migration: Don't drink an drive - Delgado et al.&nbsp;</div><div>6. Macropinocytosis in phagocyte function and immunity -&nbsp; Canton et al.&nbsp;</div><div><br></div><div>Part 2: Signaling Mechanisms Driving Macropinocytosis</div><div>7. Roles of 3' Phosphoinositides in Macropinocytosis - Swanson et al.</div><div>8. Signaling pathways that regulate macropinocytosis in mammalian cells - Palm</div><div>9. Wnt, GSK3 and Macropinocytosis - Munoz et al.</div><div>10. Kras addiction promotes cancer cell adapation in harsh microenvironment through micropinocytosis - Seguin et al.&nbsp;</div><div>11. Kras-independent macropinocytosis in pancreatic cancer - Hobbs et al.&nbsp;</div><div><br></div>

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€ 180,99
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