Ibuprofen: Pharmacology, Therapeutics and Side Effects

Gebonden Engels 2013 2012e druk 9783034804950
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Samenvatting

Ibuprofen is one of the most successful drugs used worldwide for the treatment of mild to moderate pain and various inflammatory conditions. Over the past 40 years, ibuprofen has been proven to be as safe or even safer and also as effective as the established non-steroidal anti-inflammatory drugs (NSAIDs) and the coxibs. This well-written book reviews the pharmacology, clinical uses and the various adverse effects of Ibuprofen, the disposition and unique modes of action in relation to clinical effects of the drug as well as various formulations. The use of combinations with other drugs (e.g. paracetamol, codeine, caffeine) are critically assessed and the impact of natural products and Chinese Medicines on the safety of ibuprofen.

Specificaties

ISBN13:9783034804950
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:243
Uitgever:Springer Basel
Druk:2012

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Inhoudsopgave

<p>Introduction.- Biodisposition in relation to actions.- Mechanisms of inflammation and sites of action of NSAIDs.- Clinical efficacy.- Drug derivatives and formulations.- General safety profile.- Gastro-intestinal toxicity.- Cardiovascular safety.- Renal toxicity.- Hepatic toxicity.- Other adverse reactions.- Global assessment of adverse reactions &amp; human toxicology.- Overall assessment.</p>

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        Ibuprofen: Pharmacology, Therapeutics and Side Effects