Focus on Extrapyramidal Dysfunction

Dopaminergic neurotoxicity of homocysteine and its derivatives in primary mesencephalic cultures.- MTHFR C677T polymorphism, folic acid and hyperhomocysteinemia in levodopa treated patients with Parkinson’s disease.- Screening for mutations in synaptotagmin XI in Parkinson’s disease.- Depletion and restoration of endogenous monoamines affects ?-CIT binding to serotonin but not dopamine transporters in non-human primates.- Differential executive control impairments in early Parkinson’s disease.- Simple movement sequences better correlate to levodopa plasma levels than complex ones.- Clinical effects of repetitive transcranial magnetic stimulation versus acute levodopa challenge.- Impact of apomorphine on BOLD signal during movement in normals.- Worsened motor test performance following acute apomorphine injection in previously untreated patients with Parkinson’s disease.- Transdermal lisuride delivery in the treatment of Parkinson’s disease.- Congruent deterioration of complex and simple movements in patients with Huntington’s disease.- Methyltetrahydrofolate reductase polymorphism influences onset of Huntington’s disease.- Coenzyme Q10 serum levels in Huntington’s disease.- The N-methyl-D-aspartate antagonist memantine retards progression of Huntington’s disease.- Transcranial sonography in spinocerebellar ataxia type 3.- Therapeutic strategies in Friedreich’s ataxia.- Cholecystokinin- and cholecystokinin-B-receptor gene polymorphisms in panic disorder.