Modern Genome Annotation

-Bioinformatics in Europe and the Biosapiens Network:-Gene definition; State of the art in eukaryotic gene prediction; Quality control of gene predictions:-Gene regulation and expression; Evaluating methods for protein-DNA interactions. Rationalisation of protein-DNA binding data: a biophysical approach; Annotating the human transcriptome:-Genome variation; Annotation and Genetics:-Functional annotation of proteins; Resources for functional annotation; Annotation of bacterial genomes; Data mining in genome annotation;Protein Families;Sequence to Function;Structure to Function;Molecular Class Specific Information Systems:-Protein structure prediction;Structure prediction of globular proteins;The state of the art of membrane protein structure prdiction:from sequence to 3D structure:- Protein-protein complexes, pathways and networks;Metabolic pathways, enzymes;Protein-proteine interactions;Predicting protein networks from genomic data:- Infrastructure for distributed protein annotation:-Applications;Viral bioinformatics;The ENCODE project