Alfred Wittinghofer
Ras Superfamily Small G Proteins: Biology and Mechanisms 2
Transport
Paperback Engels 2016 9783319378084
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
This second of two volumes discusses subfamily proteins which function in molecular and vesicular transport mechanisms inside the cell. In this volume the focus lies on the Rab, Ran and Arf subfamily members. As in Volume 1, the book is written by international renowned scientists in the field of small G-proteins. In elaborate reviews, biochemistry, structure, function and G-protein - effector interactions are described. Together with Volume 1 this book provides an comprehensive state-of-the-art work on small G-proteins (GTPases). It is written for Graduates and Professors in Biochemistry and Cell Biology interested in the mechanism and function of small G-proteins but are extremely valuable for those who want to move into the field.
Specificaties
ISBN13:9783319378084
Taal:Engels
Bindwijze:paperback
Uitgever:Springer International Publishing
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Inhoudsopgave
<p>Prenylation of RabGTPases, their delivery to membranes and Rab recycling.- Rab proteins and the organization of organelle membrane domains.- Effectors of Rab GTPases: Rab binding specificity and their role in coordination of Rab function and localization.- A Rab effector called the exocyst and related vesicle tether complexes.- RabGEFs and GAPs – the enigma variations.- Ran in Nucleocytoplasmic Transport.- Ran in Mitosis.- Arf proteins and their regulators: at the interface between membrane lipids and the protein trafficking machinery.- Small G Proteins: Arf family GTPases in vesicular transport.- ARF-LIKE (ARL) Proteins.- GTPase-Activating Proteins for the Arf-family Small GTPases: not only for the termination.- Rag GTPases.</p>
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