Signaling Pathways for Translation

Stress, Calcium, and Rapamycin

Gebonden Engels 2001 2001e druk 9783540417101
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Samenvatting

This volume presents the response of the eukaryotic translational apparatus to cellular stress and apoptosis, including kinases activated through both the ERK and stress-activated pathways. It further explores two agents that inhibit protein synthesis, calcium and the immunosuppressant rapamycin. Six chapters written by leading experts in the field provide both new data and comprehensive literature reviews. Both the regulation of initiation and elongation are discussed, and the mechanisms of apoptosis are related to changes in the protein synthesis machinery.

Specificaties

ISBN13:9783540417101
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:178
Uitgever:Springer Berlin Heidelberg
Druk:2001

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Inhoudsopgave

The Regulation of eIF4F During Cell Growth and Cell Death.- Regulation of the Activity of Eukaryotic Initiation Factors in Stressed Cells.- Initiation Factor eIF2? Phosphorylation in Stress Responses and Apoptosis.- Elongation Factor-2 Phosphorylation and the Regulation of Protein Synthesis by Calcium.- Phosphorylation of Mammalian eIF4E by Mnk1 and Mnk2: Tantalizing Prospects for a Role in Translation.- Control of Translation by the Target of Rapamycin Proteins.

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€ 180,99
Levertijd ongeveer 9 werkdagen
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        Signaling Pathways for Translation