Cornelis Murre
Epigenetic Regulation of Lymphocyte Development
Gebonden Engels 2012 2012e druk 9783642241024Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
The studies described in this volume serve as a starting point to familiarize one self with the multifarious differences in epigenetic designs that orchestrate the progression of developing blood cells. They also may serve as a general paradigm for the mechanisms that underpin the control of eukaryotic gene expression.
Specificaties
ISBN13:9783642241024
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:194
Uitgever:Springer Berlin Heidelberg
Druk:2012
Lezersrecensies
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Inhoudsopgave
Preface.- Roles of lineage-determining transcription factors in establishing open chromatin – lessons from high-throughput studies.- B Lymphocyte Lineage Specification, Commitment and Epigenetic Control of Transcription by Early B Cell Factor 1.- Epigenetic features that regulate IgH locus recombination and expression.- Local and global epigenetic regulation of V(D)J recombination.- Genetic and Epigenetic Regulation of TCRbeta Gene Assembly.- T-cell identity and epigenetic memory.- Encoding stability versus flexibility: Lessons learned from examining epigenetics in T helper cell differentiation.- The epigenetic landscape of lineage choice: lessons from the heritability of Cd4 and Cd8 expression.- Subject Index
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