The Double [3+2] Photocycloaddition Reaction

Paperback Engels 2013 2011e druk 9783642270437
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Jason Woolford's thesis describes for the first time, a double [3+2] photocycloaddition of alkenes onto aromatic rings. Modern synthetic chemistry relies on the ability of researchers to uncover new and more efficient ways of creating highly complex structures. This work describes a novel, environmentally friendly photochemical step that converts in one pot, trivial starting materials into otherwise difficult to construct fenstrane frameworks.  The rigid cores of these frameworks have significant potential in drug design. Moreover, the novelty of this work overtakes many other methods for the creation of chiral centres. No less than seven chiral centres are created in the photochemical step together with the formation of four carbon-carbon bonds  and multifused rings. Jason's innovative work has been the subject of several publications in peer-reviewed journals.

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ISBN13:9783642270437
Taal:Engels
Bindwijze:Paperback
Aantal pagina's:184
Uitgever:Springer Berlin Heidelberg
Druk:2011

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          The Double [3+2] Photocycloaddition Reaction