J.-C. Carel,
Paul A. Kelly
Deciphering Growth
Paperback Engels 2014 9783642421297
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. Evolution has been characterised by a dramatic increase in an organism’s body size, which is not only limited to the size of the brain.
Specificaties
ISBN13:9783642421297
Taal:Engels
Bindwijze:paperback
Uitgever:Springer Berlin Heidelberg
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Inhoudsopgave
Preface.- Evolutionary Trends in Body Size.- Sexual Dimorphism in the Growth of Homo sapiens: Facts, Inferences and Speculation.- Genetic Control of Size at Birth.- The GH/IGF-1 Axis: Insights from Animal Models.- Downstream Mechanisms of Growth Hormone Action.- Growth Hormone Receptor Signaling and Differential Actions in Target Tissues Compared To IGF-I.- IGF-I and Brain Growth: Multifarious Effects on Developing Neural Cells and Mechanisms of Action.- IGF-I Deficiency: Lessons from Human Mutations.- Putting IGF-I Biology into a Clinical Perspective.- IGF Resistance: The Role of the Type 1 IGF Receptor.- The Importance of the National Cooperative Growth Study (NCGS).- Subject Index
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