Specificity, Function, and Development of NK Cells

A. NK Receptors and Coreceptors.- Regulation of Mouse NK Cells by Structurally Divergent Inhibitory Receptors.- Stimulatory Receptors in NK and T Cells.- Killer Cell Inhibitory Receptor Expression by T Cells.- The CD94/NKG2 C-Type Lectin Receptor Complex.- Triggering of Natural Killer Cell Mediated Cytotoxicity by Costimulatory Molecules.- Fc Receptors on Natural Killer Cells.- Adhesion in NK Cell Function.- B. Activation of NK Cells and Effector Functions.- Signal Transduction During NK Cell Activation: Balancing Opposing Forces.- Effector Pathways of Natural Killer Cells.- C. Development of NK Cells.- Toward a Quantitative Analysis of the Repertoire of Class I MHC-Specific Inhibitory Receptors on Natural Killer Cells.- Ontogeny and Differentiation of Murine Natural Killer Cells and Their Receptors.- D. Role of NK Cells in Infections and Tumors.- Control of Infections by NK Cells.- Natural Killer Cells and Tumor Therapy.