Harald Stenmark
Phosphoinositides in Subcellular Targeting and Enzyme Activation
Paperback Engels 2012 9783642622991Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
Cells of the immune system are activated by a variety of stimuli that are derived from other cells, ingested material or from invading microorganisms. This issue of CTMI focuses on the mechanisms of phosphoinositide-mediated protein recruitment to intracellular membranes.
Specificaties
ISBN13:9783642622991
Taal:Engels
Bindwijze:paperback
Aantal pagina's:209
Uitgever:Springer Berlin Heidelberg
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Inhoudsopgave
Preface.- Phosphoinositide involvement in phagocytosis and phagosome maturation.- Regulation of endocytosis by phosphatidylinositol 4,5-biphosphate and ENTH proteins.- Membrane targeting by pleckstrin homology (PH) domains.- Protein targeting to endosomes and phagosomes via FYVE and PX domains.- Regulation of the actin cytoskeleton by PI(4,5)P2 and PI(3,4,5)P3.- Roles of PI3K in neutrophil function.- Nuclear phosphoinositides and their functions.- Subject index.
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