Pharmacology of Ionic Channel Function: Activators and Inhibitors

Sect.I: Voltage-Dependent Ion Channels A. Voltage-Dependent Na Channels. 1. Structure and functions of Voltage-Dependent Na+ Channels. 2. Sodium Channel Blockers and Activators. B. Voltage-Dependent Ca-Channels. 3. Classification and Function of Voltage-Gated Calcium Channels. 4. Structure of the Voltage-Dependent L-Type Calcium Channels. 5. Ca2+ Channel Antagonists and Agonists. C. Voltage-Dependent K-Channels. 6. Overview of Potassium Channel Families: Molecular Bases of the Functional Diversity. 7. Pharmacology of Voltage-Gated Potassium Channels. 8. Voltage-Gated Calcium-Modulated Potassium Channels of Large Unitary Conductance: Structure, Diversity, and Pharmacology. 9. Classical Inward Rectifying Potassium Channels: Mechanisms of Inward Rectification. 10. ATP-Dependent Potassium Channels in the Kidney. 11. Structure and Function of ATP-Sensitive K+ Channels. 12. G Protein Protein-Gated K+ Channels. 13. Potassium Channels with Two Pore Domains. 14. Cardiak K+ Channels and Inherited Long QT Syndrome. Sect. II: Ligand Operated Ion Channels. 15. Gating of Ion Channels by Transmitters: The Range of Structures of the Transmitter-Gated Channels. 16. Molecular Diversity, Structure and Function of Glutamate Receptor Channels. 17. Glutamate Receptor Ion Channels: Activators and Inhibitors . 18. Structure, Diversiy, Pharmacology and Pathology of Glycine Receptor Chloride Channels. 19. GABA A Receptor Chloride Ion Channels. 20. P2X Receptors for ATP: Classification, Distribution and Function. 21. The 5-HT 3 Receptor Channel: Function, Activation and Regulation. 22. Cyclic Nucleotide-Gated Channels: Classification, Structure and Function, Activators and Inhibitors. Sect. III: Miscellaneous Ion Channels. A. Intracellular Ca Release Channels. 23. Rynodine Receptors. 24. Regulation if IP 3 Receptor Ca 2+ Release Channels. 25. Ca 2+-Activated non Selective Cation Channels.