Acute and Long-Term Side-Effects of Radiotherapy

I. Basic Principles.- Microvasculature and Radiation Damage.- The Time Factor for Late Reactions in Radiotherapy: Repopulation or Intracellular Repair?.- The Response of Tissues to Very Low Doses per Fraction: A Reflection of Induced Repair?.- Clinically Important Factors Modifying the Response of Tumors and Normal Tissue to Radiation Therapy.- II. Radiation Response of Mucosa and Skin, Muscle and Bladder.- Dose-Response Relationships for Late Effects on Skin and Mucosa.- Early and Late Normal Tissue Injury after Postmastectomy Radiotherapy.- Muscle Injury in Experimental Intraoperative Irradiation.- An Experimental In Vivo Model in Mice to Evaluate the Change in Reservoir Function of the Urinary Bladder due to Irradiation Alone or Combined with Chemotherapy.- Combined Chemo-Radiotherapy with Carboplatin, 5-Fluorouracil and Folinic Acid for Cancer of the Urinary Bladder: Acute and Late Side-Effects.- III. Radiation Effects on Lung and Heart.- Radiopathology of the Lung: Experimental and Clinical Observations.- Diagnosis of Radiation-Pneumonitis.- Lung Effects after Total Body Irradiation of Mice and Bone Marrow Transplant Patients: Comparison of Experimental and Preliminary Clinical Data.- Experimental Studies on the Pathogenesis of Damage in the Heart.- Myocardial Infarction after Irradiation in Hodgkin’s Disease: A Review.- IV. Radiation Induced Sequelae of the Central Nervous System (CNS) and the Eye.- Experimental Radiation Damage of the Central Nervous System.- Myelopathy and Hyperfractionated Accelerated Radiotherapy: A Radiobiological Interpretation.- Irradiation-Induced Brain Dysfunction in Children.- Central Nervous System Injury from Implanted Isotopes.- Long-Term Cerebral Side-Effects of Total Body Irradiation and Quality of Life.- Eye Sequelae Following External Irradiation.- V. Particular Problems in Pediatric Radiotherapy.- Late Side Effects of Pediatric Radiotherapy.- Side-Effects After Combination Therapy for Ewing’s Sarcoma.- Subclinical Impairment of Renal Function After Radiotherapy for Hodgkin’s Disease in Children.- VI. Second Malignancies.- Incidence of Secondary Malignancies in Patients with Hodgkin’s Disease: Preliminary Results.