G. Jeanette Thorbecke,
Vincent K. Tsiagbe
The Biology of Germinal Centers in Lymphoid Tissue
Paperback Engels 2013 9783662131435
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated. Various aspects of the generation of germinal centers, the somatic hypermutation process and the cellular interactions involved in the selection process are discussed in detail. A chapter on germinal center-derived lymphomas completes the treatment.
Specificaties
ISBN13:9783662131435
Taal:Engels
Bindwijze:paperback
Aantal pagina's:241
Uitgever:Springer Berlin Heidelberg
Druk:0
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Inhoudsopgave
1. Overview of Germinal Center Function and Structure in Normal and Genetically Engineered Mice.- 2. The Germinal Center Reaction: Influence of FDC Function in Normal, Aged, and Retrovirus Infected Hosts.- 3. T and B Lymphocytes in Germinal Centers.- 4. Somatic Hypermutation of Immunoglobulin Genes.- 5. Germinal Center Derived Lymphomas in Humans and Mice.- Color Figures.
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