Optimization of Aerosol Drug Delivery

Introduction A history of the development of therapy by jet nebulisation; Ola Nerbrink Molecular modelling in drug design; Bogdan Lesyng and Witold Rudnicki Particle elaboration using supercritical media for drug delivery into the human lungs; Jerzy Baldyga and Marek Henczka Electrospray as means to produce monodisperse drug particles; Kees Geerse and Jan Marijnissen Optimization of dry powder aerosols for systemic drug delivery; Rita Vanbever Recent advances in drug delivery via pressurised metered-dose inhalers; John Pritchard Resuspension of powders and deposition of aerosol particles in the upper human airways; Leon Gradon, Tomasz Sosnowski and Arkadiusz Moskal Transport and deposition of hydrophilic drug particles in the lungs; Joachirn Heyder, Josef Gebhart, Christa Roth and George Ferron Ventilation modelling and drug deposition in very young asthmatic children; Frans de Jongh and Rupino Griffioen Modeling aerosol drug delivery; Yung Sung Cheng Application of electro hydro dynamic atomisation in the production of engineered drug particles; Tomasz Ciach, Lidia Diaz, Esther van den IJssel and Jan Marijnissen Interaction of deposited aerosol particles with the alveolar liquid layer; Tomasz Sosnowski, Leon Gradon, Ferry Iskandar and Kikuo Okuyama Pulmonary deposition and effects of aerosolized drugs in pulmonary patients; Eric Derom Targetting aerosols to disease areas; Pieter Zanen Treatment of asthma patients under severe conditions; Giuseppe Marraro Understanding the mechanisms of local pulmonary drug absorption and metabolism: An in vitro model of the airway epithelium; Gerrit Borchard Overview; Gerrit Borchard Keyword Index List of Authors