Harren Jhoti,
Andrew R. Leach
Structure-based Drug Discovery
Paperback Engels 2010 9789048171231Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
This book describes some of the most exciting developments for the discovery of new drugs, such as Fragment-based methods. It contains the latest developments in technologies that can be used to obtain the 3-D structures. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as well as other biophysical methods for studying protein/ligand interactions.
Specificaties
ISBN13:9789048171231
Taal:Engels
Bindwijze:paperback
Aantal pagina's:250
Uitgever:Springer Netherlands
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Inhoudsopgave
Five Years of Increasing Structural Biology Throughput - A Retrospective Analysis.- Protein Production for Structural Genomics - Strategies for the Next Phase.- to Fragment Screening.- Fragment-Based NMR Screening in Lead Discovery.- Fragment-Based Screening by X-ray Crystallography.- Scaffold-Based Drug Discovery.- Biophysical Methods.- Illustration of Current Challenges in Molecular Docking.- Scoring Functions.
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