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Bayesian Adaptive Design for Immunotherapy and Targeted Therapy

Paperback Engels 2024 9789811984679
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

This book provides a comprehensive review of novel adaptive trial designs for targeted therapies and immunotherapies. This book covers a wide range of novel statistical designs for various clinical settings, including early phase dose-escalation study, proof-of-concept trials, and confirmatory studies with registrational. The book includes real-life examples and software to facilitate practitioners to learn and use the designs in practice.

Specificaties

ISBN13:9789811984679
Taal:Engels
Bindwijze:paperback
Uitgever:Springer Nature Singapore

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Inhoudsopgave

Introduction to Adaptive Design and Delayed Outcomes.- Basics of Bayesian Statistics.- Phase I Dose-finding Design.- Phase II Design for Interim Monitoring.- Phase I-II Dose-finding Design.- Drug Combination Trial Design.- Conclusion.

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        Bayesian Adaptive Design for Immunotherapy and Targeted Therapy