Pathogenesis and Treatment of Leukemia

<p>Ch 1 Basic haematopoiesis and leukemia stem cells.- Ch 2 Modern classification of acute and chronic leukemias: integrating biology, clinicopathologic features and genomics.- Ch 3 Molecular techniques in the diagnosis and monitoring of acute and chronic leukemias.- Ch 4 Flow cytometric techniques in the diagnosis and monitoring of acute leukemias.- Ch 5 Genomic Landscape and Risk Stratification of Acute Myeloid Leukemia.- Ch 6 Frontline management of acute myeloid leukaemia eligible for intensive chemotherapy.- Ch 7 Frontline management of elderly acute myeloid leukemia ineligible for intensive treatment.- Ch 8 Management of Acute Myeloid Leukemia with Myelodysplasia-Related Changes and Therapy-Related Acute Myeloid Leukemia.- Ch 9 Management of relapsed or refractory AML.- Ch 10 The Role of BCL-2 / MCL-1 targeting in Acute Myeloid Leukemia.- Ch 11 Role of IDH1/IDH2 inhibitors in AML.- Ch 12 Next-generation FLT3 inhibitors for the treatment of FLT3-positive AML.- Ch 13 Allogeneic hematopoietic stem cell transplantation for AML.- Ch 14 Maintenance therapy following allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia.- Ch 15 Immunotherapeutic targeting of AML.- Ch 16 In the pipeline – Emerging therapy for acute myeloid leukaemia.- Ch 17 Frontline management of acute promyelocytic leukemia.- Ch 18 Management of relapsed acute promyelocyticleukemia and the role of hematopoietic stem cell transplantation.- Ch 19 Genomic Landscape of Acute Lymphoblastic Leukaemia (ALL) – Insights to Leukaemogenesis, Prognostications and Treatment.- Ch 20 Management of adolescent and young adults with Acute Lymphoblastic Leukaemia.- Ch 21 Management of older patients with acute lymphoblastic leukemia.- Ch 22 Management of Philadelphia Chromosome-positive Acute Lymphoblastic Leukaemia.- Ch 23 Management of Philadelphia Chromosome-like Acute Lymphoblastic Leukemia (Ph-like ALL).- Ch 24 Allogeneic Hematopoietic Stem Cell Transplantation for Acute Lymphoblastic Leukemia.- Ch 25 Immunotherapy for ALL.- Ch 26 In the Pipeline - Emerging therapy for ALL.- Ch 27 Inherited/genetic predisposition to MDS and AML.- Ch 28 Clonal hematopoiesis and its functional implications in MDS/AML.- Ch 29 Therapy-related MDS/AML and the role of environmental factors.- Ch 30 Prognostic indicators in MDS and CMML.- Ch 31 Treatment algorithm of myelodysplastic syndromes.- Ch 32 Treatment algorithm of CMML and other uncommon MDS/MPN subtypes.- Ch 33 Novel strategies to manage cytopenia in low-risk MDS.- Ch 34 Allogeneic hematopoietic stem cell transplantation for MDS and CMML: when and how?.- Ch 35 In the Pipeline - Emerging therapy for MDS and MDS/MPN.- Ch 36 Molecular landscape and personalized prognostic prediction of MPNs.- Ch 37 Treatment algorithm of polycythemia Vera.- Ch 38 Treatment algorithm of essential thrombocythemia.- Ch 39 Prognostic models for primary and secondary myelofibrosis.- Ch 40 Treatment algorithm for primary and secondary myelofibrosis.- Ch 41 Diagnosis and management of prefibrotic primary myelofibrosis (pre-PMF).- Ch 42 Interferons In myeloproliferative neoplasms.- Ch 43 JAK inhibitors for the management of myeloproliferative neoplasms.- Ch 44 Allogeneic hematopoietic stem cell transplantation for myelofibrosis – when and how?.- Ch 45 Thrombosis and myeloproliferative neoplasms.- Ch 46 Eosinophilic disorders and systemic mastocytosis.- Ch 47 In the Pipeline - Emerging therapy for classical Ph-negative MPNs.- Ch 48 Current guidelines and treatment algorithm of chronic myeloid leukaemia.- Ch 49 Treatment-free remission in chronic myeloid leukemia.- Ch 50 Treatment options in CML resistant or intolerant to second-generation tyrosine kinase inhibitors.- Ch 51 Allogeneic hematopoietic cell transplantation in CML: when and how?.- Ch 52 In the Pipeline - Emerging therapy for CML.</p>Ch 1 Basic haematopoiesis and leukemia stem cells.- Ch 2 Modern classification of acute and chronic leukemias: integrating biology, clinicopathologic features and genomics.- Ch 3 Molecular techniques in the diagnosis and monitoring of acute and chronic leukemias.- Ch 4 Flow cytometric techniques in the diagnosis and monitoring of acute leukemias.- Ch 5 Genomic Landscape and Risk Stratification of Acute Myeloid Leukemia.- Ch 6 Frontline management of acute myeloid leukaemia eligible for intensive chemotherapy.- Ch 7 Frontline management of elderly acute myeloid leukemia ineligible for intensive treatment.- Ch 8 Management of Acute Myeloid Leukemia with Myelodysplasia-Related Changes and Therapy-Related Acute Myeloid Leukemia.- Ch 9 Management of relapsed or refractory AML.- Ch 10 The Role of BCL-2 / MCL-1 targeting in Acute Myeloid Leukemia.- Ch 11 Role of IDH1/IDH2 inhibitors in AML.- Ch 12 Next-generation FLT3 inhibitors for the treatment of FLT3-positive AML.- Ch 13 Allogeneic hematopoietic stem cell transplantation for AML.- Ch 14 Maintenance therapy following allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia.- Ch 15 Immunotherapeutic targeting of AML.- Ch 16 In the pipeline – Emerging therapy for acute myeloid leukaemia.- Ch 17 Frontline management of acute promyelocytic leukemia.- Ch 18 Management of relapsed acute promyelocyticleukemia and the role of hematopoietic stem cell transplantation.- Ch 19 Genomic Landscape of Acute Lymphoblastic Leukaemia (ALL) – Insights to Leukaemogenesis, Prognostications and Treatment.- Ch 20 Management of adolescent and young adults with Acute Lymphoblastic Leukaemia.- Ch 21 Management of older patients with acute lymphoblastic leukemia.- Ch 22 Management of Philadelphia Chromosome-positive Acute Lymphoblastic Leukaemia.- Ch 23 Management of Philadelphia Chromosome-like Acute Lymphoblastic Leukemia (Ph-like ALL).- Ch 24 Allogeneic Hematopoietic Stem Cell Transplantation for Acute Lymphoblastic Leukemia.- Ch 25 Immunotherapy for ALL.- Ch 26 In the Pipeline - Emerging therapy for ALL.- Ch 27 Inherited/genetic predisposition to MDS and AML.- Ch 28 Clonalhematopoiesis and its functional implications in MDS/AML.- Ch 29 Therapy-related MDS/AML and the role of environmental factors.- Ch 30 Prognostic indicators in MDS and CMML.- Ch 31 Treatment algorithm of myelodysplastic syndromes.- Ch 32 Treatment algorithm of CMML and other uncommon MDS/MPN subtypes.- Ch 33 Novel strategies to manage cytopenia in low-risk MDS.- Ch 34 Allogeneic hematopoietic stem cell transplantation for MDS and CMML: when and how?.- Ch 35 In the Pipeline - Emerging therapy for MDS and MDS/MPN.- Ch 36 Molecular landscape and personalized prognostic prediction of MPNs.- Ch 37 Treatment algorithm of polycythemia Vera.- Ch 38 Treatment algorithm of essential thrombocythemia.- Ch 39 Prognostic models for primary and secondary myelofibrosis.- Ch 40 Treatment algorithm for primary and secondary myelofibrosis.- Ch 41 Diagnosis and management of prefibrotic primary myelofibrosis (pre-PMF).- Ch 42 Interferons In myeloproliferative neoplasms.- Ch 43 JAK inhibitors for the management of myeloproliferative neoplasms.- Ch 44 Allogeneic hematopoietic stem cell transplantation for myelofibrosis – when and how?.- Ch 45 Thrombosis and myeloproliferative neoplasms.- Ch 46 Eosinophilic disorders and systemic mastocytosis.- Ch 47 In the Pipeline - Emerging therapy for classical Ph-negative MPNs.- Ch 48 Current guidelines and treatment algorithm of chronic myeloid leukaemia.- Ch 49 Treatment-free remission in chronic myeloid leukemia.- Ch 50 Treatment options in CML resistant or intolerant to second-generation tyrosine kinase inhibitors.- Ch 51 Allogeneic hematopoietic cell transplantation in CML: when and how?.- Ch 52 In the Pipeline - Emerging therapy for CML.</p><br></p>